Gene summary for NP_000113.1
- Gene name
- excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)
- Symbol
- ERCC3 (Alias: ERCC3; BTF2; GTF2H; RAD25; TFIIH; XPB)
- NCBI GeneID
- 2071
- Organism
- Homo sapiens
Protein sequences and regions
Representative sequence
| RefSeq ID | Region | Map |  |
|---|---|---|---|
| NP_000113.1 | 1..782 |
1
1..782
782
|
Structured regions (0)
Structure mapping
Domain / Motif regions (8)
| Interpro ID | Name | Regions | Map | |
|---|---|---|---|---|
| IPR001161 (PR00851) | Xeroderma pigmentosum group B protein (XP-B) | 74..94, 160..179, 297..323, 328..350, 434..454, 500..522, 537..552, 556..578, 603..621, 622..647, 653..676, 742..761 |
1
74..94
160..179
297..323
328..350
434..454
500..522
537..552
556..578
603..621
622..647
653..676
742..761
782
|
|
| IPR001161 (TIGR00603) | Xeroderma pigmentosum group B protein (XP-B) | 60..779 |
1
60..779
782
|
|
| IPR001650 (PF00271) | DNA/RNA helicase, C-terminal | 579..647 |
1
579..647
782
|
|
| IPR001650 (PS51194) | DNA/RNA helicase, C-terminal | 542..702 |
1
542..702
782
|
|
| IPR001650 (SM00490) | DNA/RNA helicase, C-terminal | 569..647 |
1
569..647
782
|
|
| IPR006935 (PF04851) | Restriction endonuclease, type I, R subunit/Type III, Res subunit | 316..470 |
1
316..470
782
|
|
| IPR014001 (SM00487) | DEAD-like helicase, N-terminal | 312..492 |
1
312..492
782
|
|
| IPR014021 (PS51192) | Helicase, superfamily 1/2, ATP-binding domain | 327..488 |
1
327..488
782
|
Variant regions (0)
Non-synonymous SNPs (4)
Interacting regions (1)
| Interactants | Ref. | Relation | # of rec. | Region | Map | |
|---|---|---|---|---|---|---|
| SMAD2 |
|
|
1 | 682..698 |
1
682..698
782
|
Contacting amino acids (calculated from 3D structures) (0)
Custom regions (0)
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