Gene summary for NP_000113.1

Gene name
excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)
Symbol
ERCC3 (Alias: ERCC3; BTF2; GTF2H; RAD25; TFIIH; XPB)
NCBI GeneID
2071
Organism
Homo sapiens

Protein sequences and regions

Representative sequence

RefSeq ID Region Map help_icon
NP_000113.1 1..782
1
1..782
782

Structured regions (0)

Structure mapping

Domain / Motif regions (8)

Interpro ID Name Regions Map help_icon
IPR001161 (PR00851) Xeroderma pigmentosum group B protein (XP-B) 74..94, 160..179, 297..323, 328..350, 434..454, 500..522, 537..552, 556..578, 603..621, 622..647, 653..676, 742..761
1
74..94 160..179 297..323 328..350 434..454 500..522 537..552 556..578 603..621 622..647 653..676 742..761
782
IPR001161 (TIGR00603) Xeroderma pigmentosum group B protein (XP-B) 60..779
1
60..779
782
IPR001650 (PF00271) DNA/RNA helicase, C-terminal 579..647
1
579..647
782
IPR001650 (PS51194) DNA/RNA helicase, C-terminal 542..702
1
542..702
782
IPR001650 (SM00490) DNA/RNA helicase, C-terminal 569..647
1
569..647
782
IPR006935 (PF04851) Restriction endonuclease, type I, R subunit/Type III, Res subunit 316..470
1
316..470
782
IPR014001 (SM00487) DEAD-like helicase, N-terminal 312..492
1
312..492
782
IPR014021 (PS51192) Helicase, superfamily 1/2, ATP-binding domain 327..488
1
327..488
782

Variant regions (0)

Non-synonymous SNPs (4)

dbSNP ID Residue change Regions Map help_icon
rs1805161 K → R 118..118
1
118..118
782
rs1805162 G → C 403..403
1
403..403
782
rs4150521 S → L 705..705
1
705..705
782
rs4150522 S → P 736..736
1
736..736
782

Interacting regions (1)

Interactants Ref. Relation # of rec. Region Map help_icon
SMAD2 Reference Domain/Motifs
  • 17 a.a. overlap with IPR001161 (TIGR00603).
  • 17 a.a. overlap with IPR001650 (PS51194).
SNPs Structured region Variant regions Interacting regions
1 682..698
1
682..698
782

Contacting amino acids (calculated from 3D structures) (0)

Custom regions (0)

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