Gene summary for NP_000115.1
- Gene name
- excision repair cross-complementing rodent repair deficiency, complementation group 6
- Symbol
- ERCC6 (Alias: ERCC6; ARMD5; CKN2; COFS; COFS1; CSB; RAD26)
- NCBI GeneID
- 2074
- Organism
- Homo sapiens
Protein sequences and regions
Representative sequence
| RefSeq ID | Region | Map |  |
|---|---|---|---|
| NP_000115.1 | 1..1493 |
1
1..1493
1493
|
Structured regions (0)
Structure mapping
Domain / Motif regions (6)
| Interpro ID | Name | Regions | Map | |
|---|---|---|---|---|
| IPR000330 (PF00176) | SNF2-related | 510..810 |
1
510..810
1493
|
|
| IPR001650 (PF00271) | DNA/RNA helicase, C-terminal | 874..952 |
1
874..952
1493
|
|
| IPR001650 (PS51194) | DNA/RNA helicase, C-terminal | 843..1002 |
1
843..1002
1493
|
|
| IPR001650 (SM00490) | DNA/RNA helicase, C-terminal | 869..952 |
1
869..952
1493
|
|
| IPR014001 (SM00487) | DEAD-like helicase, N-terminal | 503..703 |
1
503..703
1493
|
|
| IPR014021 (PS51192) | Helicase, superfamily 1/2, ATP-binding domain | 519..695 |
1
519..695
1493
|
Variant regions (1)
| Protein ID | Type | Regions | Map | |
|---|---|---|---|---|
| Q59FF6 | missing in related sequence | 763..794 |
1
763..794
1493
|
Non-synonymous SNPs (37)
| dbSNP ID | Residue change | Regions | Map | |
|---|---|---|---|---|
| rs2228525 | T → M | 943..943 |
1
943..943
1493
|
|
| rs2228526 | M → V | 1098..1098 |
1
1098..1098
1493
|
|
| rs2228527 | R → G | 1214..1214 |
1
1214..1214
1493
|
|
| rs2228528 | G → D | 400..400 |
1
400..400
1493
|
|
| rs2228529 | Q → R | 1414..1414 |
1
1414..1414
1493
|
|
| rs2229761 | V → L | 1309..1309 |
1
1309..1309
1493
|
|
| rs34704611 | T → I | 1221..1221 |
1
1221..1221
1493
|
|
| rs34917815 | D → E | 1356..1356 |
1
1356..1356
1493
|
|
| rs41281957 | T → I | 57..57 |
1
57..57
1493
|
|
| rs41549213 | R → H | 558..558 |
1
558..558
1493
|
|
| rs41555314 | G → R | 1078..1078 |
1
1078..1078
1493
|
|
| rs41555612 | V → M | 987..987 |
1
987..987
1493
|
|
| rs41557921 | D → H | 936..936 |
1
936..936
1493
|
|
| rs41562713 | I → V | 1022..1022 |
1
1022..1022
1493
|
|
| rs4253045 | E → D | 383..383 |
1
383..383
1493
|
|
| rs4253046 | D → A | 426..426 |
1
426..426
1493
|
|
| rs4253047 | G → D | 447..447 |
1
447..447
1493
|
|
| rs4253206 | Y → C | 1003..1003 |
1
1003..1003
1493
|
|
| rs4253208 | P → R | 1096..1096 |
1
1096..1096
1493
|
|
| rs4253211 | R → P | 1231..1231 |
1
1231..1231
1493
|
|
| rs4253219 | G → V | 1323..1323 |
1
1323..1323
1493
|
|
| rs4253227 | G → R | 1373..1373 |
1
1373..1373
1493
|
|
| rs4253228 | G → R | 1383..1383 |
1
1383..1383
1493
|
|
| rs4253229 | G → R | 1411..1411 |
1
1411..1411
1493
|
|
| rs4253230 | T → I | 1442..1442 |
1
1442..1442
1493
|
|
| rs55698015 | T → M | 700..700 |
1
700..700
1493
|
|
| rs56089364 | E → G | 383..383 |
1
383..383
1493
|
|
| rs56397747 | R → H | 768..768 |
1
768..768
1493
|
|
| rs58985498 | S → C | 1330..1330 |
1
1330..1330
1493
|
|
| rs61749175 | R → C | 480..480 |
1
480..480
1493
|
|
| rs61760163 | R → C | 667..667 |
1
667..667
1493
|
|
| rs61760166 | F → C | 1218..1218 |
1
1218..1218
1493
|
|
| rs61760167 | E → A | 1409..1409 |
1
1409..1409
1493
|
|
| rs74693932 | Q → E | 279..279 |
1
279..279
1493
|
|
| rs74733025 | T → I | 906..906 |
1
906..906
1493
|
|
| rs77027474 | R → H | 838..838 |
1
838..838
1493
|
|
| rs78128107 | R → S | 895..895 |
1
895..895
1493
|
Interacting regions (2)
Contacting amino acids (calculated from 3D structures) (0)
Custom regions (0)
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