Gene summary for NP_000115.1

Gene name
excision repair cross-complementing rodent repair deficiency, complementation group 6
Symbol
ERCC6 (Alias: ERCC6; ARMD5; CKN2; COFS; COFS1; CSB; RAD26)
NCBI GeneID
2074
Organism
Homo sapiens

Protein sequences and regions

Representative sequence

RefSeq ID Region Map help_icon
NP_000115.1 1..1493
1
1..1493
1493

Structured regions (0)

Structure mapping

Domain / Motif regions (6)

Interpro ID Name Regions Map help_icon
IPR000330 (PF00176) SNF2-related 510..810
1
510..810
1493
IPR001650 (PF00271) DNA/RNA helicase, C-terminal 874..952
1
874..952
1493
IPR001650 (PS51194) DNA/RNA helicase, C-terminal 843..1002
1
843..1002
1493
IPR001650 (SM00490) DNA/RNA helicase, C-terminal 869..952
1
869..952
1493
IPR014001 (SM00487) DEAD-like helicase, N-terminal 503..703
1
503..703
1493
IPR014021 (PS51192) Helicase, superfamily 1/2, ATP-binding domain 519..695
1
519..695
1493

Variant regions (1)

Protein ID Type Regions Map help_icon
Q59FF6 missing in related sequence 763..794
1
763..794
1493

Non-synonymous SNPs (37)

dbSNP ID Residue change Regions Map help_icon
rs2228525 T → M 943..943
1
943..943
1493
rs2228526 M → V 1098..1098
1
1098..1098
1493
rs2228527 R → G 1214..1214
1
1214..1214
1493
rs2228528 G → D 400..400
1
400..400
1493
rs2228529 Q → R 1414..1414
1
1414..1414
1493
rs2229761 V → L 1309..1309
1
1309..1309
1493
rs34704611 T → I 1221..1221
1
1221..1221
1493
rs34917815 D → E 1356..1356
1
1356..1356
1493
rs41281957 T → I 57..57
1
57..57
1493
rs41549213 R → H 558..558
1
558..558
1493
rs41555314 G → R 1078..1078
1
1078..1078
1493
rs41555612 V → M 987..987
1
987..987
1493
rs41557921 D → H 936..936
1
936..936
1493
rs41562713 I → V 1022..1022
1
1022..1022
1493
rs4253045 E → D 383..383
1
383..383
1493
rs4253046 D → A 426..426
1
426..426
1493
rs4253047 G → D 447..447
1
447..447
1493
rs4253206 Y → C 1003..1003
1
1003..1003
1493
rs4253208 P → R 1096..1096
1
1096..1096
1493
rs4253211 R → P 1231..1231
1
1231..1231
1493
rs4253219 G → V 1323..1323
1
1323..1323
1493
rs4253227 G → R 1373..1373
1
1373..1373
1493
rs4253228 G → R 1383..1383
1
1383..1383
1493
rs4253229 G → R 1411..1411
1
1411..1411
1493
rs4253230 T → I 1442..1442
1
1442..1442
1493
rs55698015 T → M 700..700
1
700..700
1493
rs56089364 E → G 383..383
1
383..383
1493
rs56397747 R → H 768..768
1
768..768
1493
rs58985498 S → C 1330..1330
1
1330..1330
1493
rs61749175 R → C 480..480
1
480..480
1493
rs61760163 R → C 667..667
1
667..667
1493
rs61760166 F → C 1218..1218
1
1218..1218
1493
rs61760167 E → A 1409..1409
1
1409..1409
1493
rs74693932 Q → E 279..279
1
279..279
1493
rs74733025 T → I 906..906
1
906..906
1493
rs77027474 R → H 838..838
1
838..838
1493
rs78128107 R → S 895..895
1
895..895
1493

Interacting regions (2)

Interactants Ref. Relation # of rec. Region Map help_icon
TRIM3 Reference Domain/Motifs SNPs Structured region Variant regions Interacting regions 1 106..152
1
106..152
1493
NFKB1 Reference Domain/Motifs SNPs
  • SNP:rs61749175 (Pos=480) falls into interacting region.
Structured region Variant regions Interacting regions
1 454..487
1
454..487
1493

Contacting amino acids (calculated from 3D structures) (0)

Custom regions (0)

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