Gene summary for NP_000798.1

Gene name
gamma-aminobutyric acid (GABA) A receptor, alpha 2
Symbol
GABRA2 (Alias: GABRA2; FLJ97076)
NCBI GeneID
2555
Organism
Homo sapiens

Protein sequences and regions

Representative sequence

RefSeq ID Region Map help_icon
NP_000798.1 1..451
1
1..451
451

Structured regions (0)

Structure mapping

Domain / Motif regions (12)

Interpro ID Name Regions Map help_icon
IPR001390 (PR01079) Gamma-aminobutyric-acid A receptor, alpha subunit 40..51, 60..77, 104..116, 196..208, 213..235, 306..319, 410..422, 435..446
1
40..51 60..77 104..116 196..208 213..235 306..319 410..422 435..446
451
IPR005432 (PR01615) Gamma-aminobutyric-acid A receptor, alpha 2 subunit 9..9, 12..27, 347..362, 366..380, 384..408
1
9..9 12..27 347..362 366..380 384..408
451
IPR006028 (PR00253) Gamma-aminobutyric acid A receptor 253..273, 279..300, 313..334, 420..440
1
253..273 279..300 313..334 420..440
451
IPR006029 (PF02932) Neurotransmitter-gated ion-channel transmembrane domain 257..340, 358..437
1
257..340 358..437
451
IPR006029 (SSF90112) Neurotransmitter-gated ion-channel transmembrane domain 250..342, 344..447
1
250..342 344..447
451
IPR006201 (PTHR18945) Neurotransmitter-gated ion-channel 58..342, 344..444
1
58..342 344..444
451
IPR006201 (TIGR00860) Neurotransmitter-gated ion-channel 12..342, 344..440
1
12..342 344..440
451
IPR006202 (G3DSA:2.70.170.10) Neurotransmitter-gated ion-channel ligand-binding 40..255
1
40..255
451
IPR006202 (PF02931) Neurotransmitter-gated ion-channel ligand-binding 43..250
1
43..250
451
IPR006202 (PR00252) Neurotransmitter-gated ion-channel ligand-binding 88..104, 120..131, 166..180, 244..256
1
88..104 120..131 166..180 244..256
451
IPR006202 (SSF63712) Neurotransmitter-gated ion-channel ligand-binding 40..250
1
40..250
451
IPR018000 (PS00236) Neurotransmitter-gated ion-channel, conserved site 166..180
1
166..180
451

Variant regions (0)

Non-synonymous SNPs (0)

Interacting regions (1)

Interactants Ref. Relation # of rec. Region Map help_icon
MDM2 Reference Domain/Motifs
  • 7 a.a. overlap with IPR005432 (PR01615).
  • 10 a.a. overlap with IPR006029 (SSF90112).
  • 10 a.a. overlap with IPR006201 (PTHR18945).
  • 10 a.a. overlap with IPR006201 (TIGR00860).
SNPs Structured region Variant regions Interacting regions
1 344..353
1
344..353
451

Contacting amino acids (calculated from 3D structures) (0)

Custom regions (0)

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