Gene summary for NP_000933.1

Gene name
peptidylprolyl isomerase B (cyclophilin B)
Symbol
PPIB (Alias: PPIB; CYP-S1; CYPB; MGC14109; MGC2224; OI9; SCYLP)
NCBI GeneID
5479
Organism
Homo sapiens

Protein sequences and regions

Representative sequence

RefSeq ID Region Map help_icon
NP_000933.1 1..216
1
1..216
216

Structured regions (1)

PDB ID Chain Regions Mapppp help_icon
1CYN A 15..192
1
15..192
216

Domain / Motif regions (6)

Interpro ID Name Regions Map help_icon
IPR002130 (G3DSA:2.40.100.10) Peptidyl-prolyl cis-trans isomerase, cyclophilin-type 50..214
1
50..214
216
IPR002130 (PF00160) Peptidyl-prolyl cis-trans isomerase, cyclophilin-type 57..211
1
57..211
216
IPR002130 (PR00153) Peptidyl-prolyl cis-trans isomerase, cyclophilin-type 72..87, 101..113, 144..159, 159..171, 172..187
1
72..87 101..113 144..159 159..171 172..187
216
IPR002130 (PS50072) Peptidyl-prolyl cis-trans isomerase, cyclophilin-type 55..212
1
55..212
216
IPR015891 (SSF50891) Cyclophilin-like 49..214
1
49..214
216
IPR020892 (PS00170) Peptidyl-prolyl cis-trans isomerase, cyclophilin-type, conserved site 96..113
1
96..113
216

Variant regions (0)

Non-synonymous SNPs (2)

dbSNP ID Residue change Regions Map help_icon
rs11558595 V → L 61..61
1
61..61
216
rs1804427 V → A 208..208
1
208..208
216

Interacting regions (1)

Interactants Ref. Relation # of rec. Region Map help_icon
NR4A1 Reference Domain/Motifs
  • 142 a.a. overlap with IPR002130 (G3DSA:2.40.100.10).
  • 135 a.a. overlap with IPR002130 (PF00160).
  • 74 a.a. overlap with IPR002130 (PR00153).
  • 137 a.a. overlap with IPR002130 (PS50072).
  • 143 a.a. overlap with IPR015891 (SSF50891).
  • 18 a.a. overlap with IPR020892 (PS00170).
SNPs
  • SNP:rs11558595 (Pos=61) falls into interacting region.
Structured region
  • 177 a.a. overlap with 1CYN:A.
Variant regions Interacting regions
1 3..191
1
3..191
216

Contacting amino acids (calculated from 3D structures) (0)

Custom regions (0)

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