Gene summary for NP_005243.1

Gene name
FBJ murine osteosarcoma viral oncogene homolog
Symbol
FOS (Alias: FOS; AP-1; C-FOS)
NCBI GeneID
2353
Organism
Homo sapiens

Protein sequences and regions

Representative sequence

RefSeq ID Region Map help_icon
NP_005243.1 1..380
1
1..380
380

Structured regions (3)

PDB ID Chain Regions Mapppp help_icon
1A02 F 140..192
1
140..192
380
1FOS E 139..198
1
139..198
380
1S9K D 140..192
1
140..192
380

Domain / Motif regions (5)

Interpro ID Name Regions Map help_icon
IPR000837 (PR00042) Fos transforming protein 62..79, 130..146, 147..163, 165..186, 186..209
1
62..79 130..146 147..163 165..186 186..209
380
IPR004827 (PS00036) Basic-leucine zipper (bZIP) transcription factor 143..157
1
143..157
380
IPR004827 (PS50217) Basic-leucine zipper (bZIP) transcription factor 137..200
1
137..200
380
IPR004827 (SM00338) Basic-leucine zipper (bZIP) transcription factor 135..199
1
135..199
380
IPR011616 (PF00170) bZIP transcription factor, bZIP-1 135..194
1
135..194
380

Variant regions (0)

Non-synonymous SNPs (3)

dbSNP ID Residue change Regions Map help_icon
rs66753615 A → P 101..101
1
101..101
380
rs67663275 P → G 127..127
1
127..127
380
rs67832909 L → I 194..194
1
194..194
380

Interacting regions (40)

Interactants Ref. Relation # of rec. Region Map help_icon
JUN Reference Domain/Motifs
  • 98 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
2 1..251
1
1..251
380
JUN Reference Domain/Motifs
  • 98 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 1..347
1
1..347
380
JUNB Reference Domain/Motifs
  • 98 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUN interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 1..347
1
1..347
380
JUN Reference Domain/Motifs
  • 98 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 1..348
1
1..348
380
JUN Reference Domain/Motifs
  • 98 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
5 1..380
1
1..380
380
JUND Reference Domain/Motifs
  • 98 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUN interacting region.
  • overlap with JUNB interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
2 1..380
1
1..380
380
SMAD2 Reference Domain/Motifs
  • 15 a.a. overlap with IPR000837 (PR00042).
  • 2 a.a. overlap with IPR004827 (PS00036).
  • 8 a.a. overlap with IPR004827 (PS50217).
  • 10 a.a. overlap with IPR004827 (SM00338).
  • 10 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67663275 (Pos=127) falls into interacting region.
Structured region
  • 5 a.a. overlap with 1A02:F.
  • 6 a.a. overlap with 1FOS:E.
  • 5 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUN interacting region.
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 112..144
1
112..144
380
JUN Reference Domain/Motifs
  • 80 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
3 114..380
1
114..380
380
JUND Reference Domain/Motifs
  • 80 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUN interacting region.
  • overlap with JUNB interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 114..380
1
114..380
380
JUN Reference Domain/Motifs
  • 80 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 117..380
1
117..380
380
JUND Reference Domain/Motifs
  • 80 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUN interacting region.
  • overlap with JUNB interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 117..380
1
117..380
380
JUN Reference Domain/Motifs
  • 80 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 119..380
1
119..380
380
JUN Reference Domain/Motifs
  • 80 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 120..380
1
120..380
380
JUN Reference Domain/Motifs
  • 80 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
2 130..380
1
130..380
380
JUND Reference Domain/Motifs
  • 80 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUN interacting region.
  • overlap with JUNB interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 130..380
1
130..380
380
JUN Reference Domain/Motifs
  • 71 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 62 a.a. overlap with IPR004827 (PS50217).
  • 61 a.a. overlap with IPR004827 (SM00338).
  • 56 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 139..259
1
139..259
380
ISL1 Reference Domain/Motifs
  • 69 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 60 a.a. overlap with IPR004827 (PS50217).
  • 59 a.a. overlap with IPR004827 (SM00338).
  • 54 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 52 a.a. overlap with 1A02:F.
  • 58 a.a. overlap with 1FOS:E.
  • 52 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUN interacting region.
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with PRMT2 interacting region.
1 141..380
1
141..380
380
JUND Reference Domain/Motifs
  • 69 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 60 a.a. overlap with IPR004827 (PS50217).
  • 59 a.a. overlap with IPR004827 (SM00338).
  • 54 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 52 a.a. overlap with 1A02:F.
  • 58 a.a. overlap with 1FOS:E.
  • 52 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUN interacting region.
  • overlap with JUNB interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 141..380
1
141..380
380
JUND Reference Domain/Motifs
  • 65 a.a. overlap with IPR000837 (PR00042).
  • 13 a.a. overlap with IPR004827 (PS00036).
  • 56 a.a. overlap with IPR004827 (PS50217).
  • 55 a.a. overlap with IPR004827 (SM00338).
  • 50 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 48 a.a. overlap with 1A02:F.
  • 54 a.a. overlap with 1FOS:E.
  • 48 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUN interacting region.
  • overlap with JUNB interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 145..380
1
145..380
380
JUN Reference Domain/Motifs
  • 63 a.a. overlap with IPR000837 (PR00042).
  • 11 a.a. overlap with IPR004827 (PS00036).
  • 54 a.a. overlap with IPR004827 (PS50217).
  • 53 a.a. overlap with IPR004827 (SM00338).
  • 48 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 46 a.a. overlap with 1A02:F.
  • 52 a.a. overlap with 1FOS:E.
  • 46 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 147..380
1
147..380
380
JUN Reference Domain/Motifs
  • 61 a.a. overlap with IPR000837 (PR00042).
  • 9 a.a. overlap with IPR004827 (PS00036).
  • 52 a.a. overlap with IPR004827 (PS50217).
  • 51 a.a. overlap with IPR004827 (SM00338).
  • 46 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 44 a.a. overlap with 1A02:F.
  • 50 a.a. overlap with 1FOS:E.
  • 44 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 149..266
1
149..266
380
JUN Reference Domain/Motifs
  • 55 a.a. overlap with IPR000837 (PR00042).
  • 3 a.a. overlap with IPR004827 (PS00036).
  • 46 a.a. overlap with IPR004827 (PS50217).
  • 45 a.a. overlap with IPR004827 (SM00338).
  • 40 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 38 a.a. overlap with 1A02:F.
  • 44 a.a. overlap with 1FOS:E.
  • 38 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 155..233
1
155..233
380
JUN Reference Domain/Motifs
  • 43 a.a. overlap with IPR000837 (PR00042).
  • 33 a.a. overlap with IPR004827 (PS50217).
  • 32 a.a. overlap with IPR004827 (SM00338).
  • 27 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 25 a.a. overlap with 1A02:F.
  • 31 a.a. overlap with 1FOS:E.
  • 25 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 168..380
1
168..380
380
JUND Reference Domain/Motifs
  • 43 a.a. overlap with IPR000837 (PR00042).
  • 33 a.a. overlap with IPR004827 (PS50217).
  • 32 a.a. overlap with IPR004827 (SM00338).
  • 27 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 25 a.a. overlap with 1A02:F.
  • 31 a.a. overlap with 1FOS:E.
  • 25 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUN interacting region.
  • overlap with JUNB interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 168..380
1
168..380
380
JUN Reference Domain/Motifs
  • 38 a.a. overlap with IPR000837 (PR00042).
  • 28 a.a. overlap with IPR004827 (PS50217).
  • 27 a.a. overlap with IPR004827 (SM00338).
  • 22 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 20 a.a. overlap with 1A02:F.
  • 26 a.a. overlap with 1FOS:E.
  • 20 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 173..262
1
173..262
380
JUND Reference Domain/Motifs
  • 34 a.a. overlap with IPR000837 (PR00042).
  • 24 a.a. overlap with IPR004827 (PS50217).
  • 23 a.a. overlap with IPR004827 (SM00338).
  • 18 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 16 a.a. overlap with 1A02:F.
  • 22 a.a. overlap with 1FOS:E.
  • 16 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUN interacting region.
  • overlap with JUNB interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 177..380
1
177..380
380
JUN Reference Domain/Motifs
  • 98 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 3..280
1
3..280
380
JUN Reference Domain/Motifs
  • 98 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 38..280
1
38..280
380
PRMT2 Reference Domain/Motifs
  • 97 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUN interacting region.
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
1 63..234
1
63..234
380
JUN Reference Domain/Motifs
  • 97 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 63..234
1
63..234
380
JUN Reference Domain/Motifs
  • 97 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
2 63..380
1
63..380
380
JUN Reference Domain/Motifs
  • 88 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 72..380
1
72..380
380
JUN Reference Domain/Motifs
  • 82 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 78..380
1
78..380
380
JUN Reference Domain/Motifs
  • 87 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 62 a.a. overlap with IPR004827 (PS50217).
  • 64 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 8..198
1
8..198
380
JUN Reference Domain/Motifs
  • 98 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 8..275
1
8..275
380
JUN Reference Domain/Motifs
  • 80 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 84..380
1
84..380
380
JUN Reference Domain/Motifs
  • 80 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 94..315
1
94..315
380
JUNB Reference Domain/Motifs
  • 80 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUN interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 94..315
1
94..315
380
JUN Reference Domain/Motifs
  • 80 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUNB interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 95..280
1
95..280
380
JUNB Reference Domain/Motifs
  • 80 a.a. overlap with IPR000837 (PR00042).
  • 15 a.a. overlap with IPR004827 (PS00036).
  • 64 a.a. overlap with IPR004827 (PS50217).
  • 65 a.a. overlap with IPR004827 (SM00338).
  • 60 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs66753615 (Pos=101) falls into interacting region.
  • SNP:rs67663275 (Pos=127) falls into interacting region.
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 53 a.a. overlap with 1A02:F.
  • 60 a.a. overlap with 1FOS:E.
  • 53 a.a. overlap with 1S9K:D.
Variant regions Interacting regions
  • overlap with JUN interacting region.
  • overlap with JUND interacting region.
  • overlap with SMAD2 interacting region.
  • overlap with ISL1 interacting region.
  • overlap with PRMT2 interacting region.
1 95..280
1
95..280
380

Contacting amino acids (calculated from 3D structures) (5)

Interactants Structure Relation Chain Region Map help_icon
JUN 1A02:J Domain/Motifs
  • 34 a.a. overlap with IPR000837 (PR00042).
  • 2 a.a. overlap with IPR004827 (PS00036).
  • 34 a.a. overlap with IPR004827 (PS50217).
  • 34 a.a. overlap with IPR004827 (SM00338).
  • 34 a.a. overlap with IPR011616 (PF00170).
SNPs Structured region
  • 34 a.a. overlap with 1A02:F.
  • 34 a.a. overlap with 1FOS:E.
  • 34 a.a. overlap with 1S9K:D.
Variant regions
F 155..155, 157..159, 161..177, 179..180, 182..192
1
155..155 157..159 161..177 179..180 182..192
380
NFATC2 1A02:N Domain/Motifs
  • 23 a.a. overlap with IPR000837 (PR00042).
  • 24 a.a. overlap with IPR004827 (PS50217).
  • 24 a.a. overlap with IPR004827 (SM00338).
  • 24 a.a. overlap with IPR011616 (PF00170).
SNPs Structured region
  • 24 a.a. overlap with 1A02:F.
  • 24 a.a. overlap with 1FOS:E.
  • 24 a.a. overlap with 1S9K:D.
Variant regions
F 160..160, 163..164, 166..182, 184..185, 188..188, 191..191
1
160..160 163..164 166..182 184..185 188..188 191..191
380
JUN 1FOS:F Domain/Motifs
  • 41 a.a. overlap with IPR000837 (PR00042).
  • 2 a.a. overlap with IPR004827 (PS00036).
  • 41 a.a. overlap with IPR004827 (PS50217).
  • 41 a.a. overlap with IPR004827 (SM00338).
  • 38 a.a. overlap with IPR011616 (PF00170).
SNPs
  • SNP:rs67832909 (Pos=194) falls into interacting region.
Structured region
  • 36 a.a. overlap with 1A02:F.
  • 41 a.a. overlap with 1FOS:E.
  • 36 a.a. overlap with 1S9K:D.
Variant regions
E 155..155, 157..159, 161..197
1
155..155 157..159 161..197
380
NFATC2 1S9K:C Domain/Motifs
  • 23 a.a. overlap with IPR000837 (PR00042).
  • 24 a.a. overlap with IPR004827 (PS50217).
  • 24 a.a. overlap with IPR004827 (SM00338).
  • 24 a.a. overlap with IPR011616 (PF00170).
SNPs Structured region
  • 24 a.a. overlap with 1A02:F.
  • 24 a.a. overlap with 1FOS:E.
  • 24 a.a. overlap with 1S9K:D.
Variant regions
D 160..160, 163..164, 166..182, 184..185, 188..188, 191..191
1
160..160 163..164 166..182 184..185 188..188 191..191
380
JUN 1S9K:E Domain/Motifs
  • 33 a.a. overlap with IPR000837 (PR00042).
  • 1 a.a. overlap with IPR004827 (PS00036).
  • 33 a.a. overlap with IPR004827 (PS50217).
  • 33 a.a. overlap with IPR004827 (SM00338).
  • 33 a.a. overlap with IPR011616 (PF00170).
SNPs Structured region
  • 33 a.a. overlap with 1A02:F.
  • 33 a.a. overlap with 1FOS:E.
  • 33 a.a. overlap with 1S9K:D.
Variant regions
D 155..155, 158..159, 161..177, 179..180, 182..192
1
155..155 158..159 161..177 179..180 182..192
380

Custom regions (0)

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